A potential new procedure called PRP ovarian rejuvenation aims to improve fertility in women who have decreased ovarian reserve. Platelet-rich plasma (PRP) and stem cell therapy are two of the innovative advances in reproductive treatment that are utilised in ovarian rejuvenation therapy.Because of its novel approach to restoring ovarian function, this surgery has great promise for women with a range of reproductive problems, such as early ovarian failure, decreased ovarian reserve, and infertility brought on by cancer.
PRP ovarian rejuvenation is a popular natural method used by many women to increase ovarian function and increase their chances of becoming pregnant.
What is Ovarian Insufficiency?
It was often believed in the past that egg donation was the only method of conception if ovarian eggs were exhausted for any reason. The fact that the mother does not give her own genetic material to the child through egg donation is a major disadvantage. can make decision-making difficult for potential parents, particularly in religious situations where such activities may be forbidden.
But there is new hope thanks to recent developments in stem cell and Platelet-Rich Plasma (PRP) technologies. Understanding Ovarian Rejuvenation
The goal of ovarian rejuvenation is to treat issues with fertility brought on by advanced age or particular medical disorders. In order to improve the chances of conception and pregnancy, the therapy stimulates the ovaries to create more and better eggs. In order to promote tissue regeneration and egg production, platelet-rich plasma is injected directly into the ovaries during PRP ovarian rejuvenation.
Purpose of Ovarian Rejuvenation Techniques
Enhancing a woman’s egg production in terms of quality and quantity is the primary goal of ovarian rejuvenation. By doing this, it might increase fertility, postpone menopause, and lessen ovarian ageing symptoms. The goal of this treatment is to assist patients in conceiving with their own eggs.
Step-by-Step Process of Ovarian Rejuvenation Therapy
1. Consultation & Evaluation:
A comprehensive consultation and evaluation by a fertility professional marks the start of the journey. In this first phase, the patient’s medical history is examined, reproductive objectives are discussed, and maybe diagnostic testing is carried out.
2. Extraction:
The first step in producing Platelet-Rich Plasma (PRP) in PRP therapy is taking a patient’s blood. In order to use stem cell therapy, a surgical technique carried out under anaesthesia is used to remove stem cells from the patient’s adipose tissue or bone marrow.
3. Preparation:
To create PRP rich in growth factors, collected blood is processed in a centrifuge to separate platelets and plasma from other blood components. The stem cells used in stem cell therapy are separated and ready for transplantation.
4. Transplantation:
Using prepared PRP, the ovaries are directly injected during PRP therapy. In order to provide stem cell therapy, a laparoscopic procedure is used to inject the stem cells into the ovaries; this requires exact needle angulation to target the ovarian cortex. An orthopaedic surgeon with expertise in this field performs the surgery to extract stem cells using a bone marrow aspiration needle. There is still research to identify the most advantageous stem cells.
5. Post-Procedure Care:
Following a procedure, patients are closely observed in order to evaluate the efficacy of the treatment and address any possible side effects.
6. Follow-up & Monitoring:
To monitor changes in hormone levels, menstruation patterns, and other markers of better ovarian function, routine follow-up visits are essential.
The Role of Growth Factors in Rejuvenation
Growth factors are naturally produced by body cells and are necessary for both cell division and differentiation. For the regeneration of tissue, including muscle, bone, organ growth, and wound healing, these elements are essential. In order to facilitate tissue repair, plasma platelets also produce a variety of growth factors.
In surgical settings, platelet-rich plasma (PRP) has proven to be an effective treatment for sports-related injuries and for improving wound healing. This similar capacity is used to strengthen the endometrial lining in situations where the endometrium is thin and to encourage egg regeneration in the ovaries.
When considering alternative reproductive therapies, women with limited ovarian reserve are frequently advised to undergo PRP ovarian rejuvenation. PRP contains a variety of growth factors that support the rejuvenation of the ovaries, particularly in women going through menopause or early ovarian failure.
Among the Important Growth Factors Are:
- Growth Factor Derived from Platelets (PDGF)
- Transforming Growth Factor (TGF)
- Interleukin (IL)
- Platelet Factor
- Angiogenesis Factor Derived from Platelets (PDAF)
- VEGF, or vascular endothelial growth factor
- Growth Factor Epidermal (EGF)
- Fibronectin and Insulin-Like Growth Factor (IGF)
Benefits:
PRP Ovarian Rejuvenation is a minimally invasive procedure that may offer hope to women struggling with infertility. For women going through menopause and those with early ovarian failure, this therapy has shown to be quite beneficial worldwide.
Through this treatment, couples can become biological parents and start a new cycle of egg production and menstrual cycles. Numerous successful pregnancies have been documented after this treatment. By promoting the repair of ovarian tissue, PRP Ovarian Rejuvenation could extend reproductive lifespan for women facing premature ovarian aging.
Ovarian Rejuvenation Therapy: A Promising Yet Experimental Treatment
Ovarian rejuvenation therapy has potential, it is still in its early stages and may not be appropriate for all patients. It is imperative that you seek advice from a licensed fertility doctor in Delhi, or any other Indian city, prior to beginning this medication.
Leading reproductive medicine specialist Dr. Rita Bakshi provides ovarian rejuvenation therapy in Delhi.
Success Rate of Stem Cell Therapy in Ovarian Rejuvenation
Research is currently ongoing to determine the effectiveness of stem cell therapy for ovarian rejuvenation. initial findings have been positive, individual reactions may differ. According to current estimations, the success rate is between 15% and 20%.
PRP Ovarian Rejuvenation at specialized clinics like Risaa IVF offers a personalized approach to fertility enhancement and reproductive health
This blog is reviewed by Dr. Rita Bakshi who has over 40 years of experience in treating diseases like (IVF Treatment) (IUI Treatment) (ICSI Treatment) in India.